Ostenil Plus: Hyaluronic Acid with Mannitol Protection
Ostenil Plus 40mg/2ml by TRB Chemedica is a highly concentrated hyaluronic acid pre-filled syringe with a crucial addition: mannitol. This sugar alcohol acts as an antioxidant and protects the hyaluronic acid from oxidative degradation in the joint – for a prolonged duration of action and improved effectiveness.
What makes Ostenil Plus special?
Highly concentrated hyaluronic acid
With 40 mg of sodium hyaluronate in 2 ml (20 mg/ml), Ostenil Plus offers a significantly higher concentration than classic preparations such as Ostenil 20mg/2ml. The higher concentration improves the viscoelastic properties in the joint.
Mannitol as an antioxidant
Free radicals in an inflamed joint rapidly degrade hyaluronic acid. Mannitol neutralizes these free radicals, thereby prolonging the residence time of hyaluronic acid in the joint. Clinical studies show a significantly longer duration of action compared to preparations without mannitol.
Indications
- Knee osteoarthritis (gonarthrosis) Grade I–III
- Hip osteoarthritis (coxarthrosis)
- Shoulder osteoarthritis
- Ankle osteoarthritis
- Other large joints
Product Data
- Active ingredient: Sodium hyaluronate 20 mg/ml
- Volume: 2 ml per pre-filled syringe
- Additive: Mannitol (antioxidant)
- Treatment regimen: 3–5 injections at weekly intervals
- Manufacturer: TRB Chemedica (Switzerland)
- Approval: CE certified, MDR compliant
Comparison: Ostenil Plus vs. Ostenil vs. Single-Shot Preparations
| Feature | Ostenil Plus 40mg/2ml | Ostenil 20mg/2ml | Durolane 60mg/3ml |
|---|---|---|---|
| HA Concentration | 20 mg/ml | 10 mg/ml | 20 mg/ml |
| Mannitol | Yes | No | No |
| Injections | 3–5 | 3–5 | 1 |
| Duration of action | Up to 9 months | 3–6 months | Up to 6 months |
| Indication | Large joints | Large joints | Knee & Hip |
Treatment Protocol
The standard treatment comprises 3–5 intra-articular injections at weekly intervals. If well tolerated, treatment can be repeated after 6–9 months. The injection should be performed under sterile conditions, ideally ultrasound-guided.
When is Ostenil Plus the right choice?
- Patients with moderate to advanced osteoarthritis
- Patients who have already responded to simple HA preparations
- Joints with increased inflammatory activity (oxidative stress)
- Desire for a longer duration of action than standard HA
Conclusion
Ostenil Plus 40mg/2ml is the optimized further development of classic hyaluronic acid therapy. The mannitol additive makes it particularly effective in inflammatory forms of osteoarthritis and significantly prolongs the duration of action.
Order now: Ostenil Plus 40mg/2ml – in the Novamedo shop, CE certified, fast delivery, for medical professionals.
