Ellansé vs. Sculptra vs. Radiesse: Which Biostimulator is Right?

Collagen biostimulators are among the most effective anti-aging treatments – but which product suits which patient? An objective comparison for medical professionals.

Quick Comparison

Feature Ellansé Sculptra Radiesse®
Active Ingredient PCL (Polycaprolactone) PLLA (Poly-L-lactic acid) CaHA (Calcium hydroxylapatite)
Manufacturer Sinclair Pharma Galderma Merz Pharma
Duration of Effect 2–4 years 2+ years 12–18 months
Onset of Action Immediate + long-term Gradual (weeks) Immediate + long-term
Injections 1 session 2–3 sessions 1 session
Biodegradable Yes (slow) Yes Yes
Approval CE certified CE certified CE certified

Ellansé – Longest Duration of Effect

Ellansé, based on PCL, offers the longest duration of effect among all biostimulators (2–4 years) and combines immediate volume with long-term collagen stimulation. Ideal for:

  • Patients who desire long-term results
  • Facial volume & contouring
  • Reduction in treatment frequency

Sculptra – The Classic

Sculptra, based on PLLA, is the most proven biostimulator with over 20 years of clinical experience. Gradual build-up over several sessions. Ideal for:

  • Diffuse volume loss throughout the face
  • Patients who prefer natural, gradual results
  • Body applications (e.g., glutes, hands)

Radiesse® – Immediate Effect + Stimulation

Radiesse®, based on CaHA, offers immediate volume correction combined with collagen stimulation – in one session. Ideal for:

  • Nasolabial folds & marionette lines
  • Hand rejuvenation
  • Patients who desire immediate results
  • Combination with HA fillers

All Three Biostimulators at Novamedo

Novamedo offers all three products at attractive B2B prices for doctors and clinics – CE certified, original goods, delivery in 2–3 working days.

Buy Radiesse®

⚠ Exclusively for qualified medical professionals.