Sculptra PLLA: Collagen Stimulator for Natural Facial Rejuvenation

Sculptra 2 Vials by Galderma: PLLA collagen stimulator with up to 24 months of efficacy. Treatment protocol, 5-5-5 massage rule, and comparison with Radiesse & Ellansé.

Sculptra: The Long-Lasting Biostimulator from Galderma

Sculptra 2 Vials from Galderma is the leading Poly-L-Lactic Acid (PLLA) collagen stimulator – with the longest duration of action among all biostimulators and the most natural, gradual result.

What is Poly-L-Lactic Acid (PLLA)?

PLLA is a biodegradable, synthetic polymer that has been used in medicine for decades (e.g., absorbable sutures). In Sculptra, PLLA stimulates the body's own collagen production – without acting as a filler itself.

  • No Immediate Effect: Sculptra does not provide immediate volume – the result develops over 3–6 months
  • Collagen Stimulation: PLLA microparticles activate fibroblasts to produce collagen
  • Biodegradable: PLLA is completely broken down over 2 years
  • Duration of Action: Up to 24 months – longest duration of action of all biostimulators

Product Profile: Sculptra 2 Vials

  • Active Ingredient: Poly-L-Lactic Acid (PLLA) microparticles
  • Contents: 2 Vials per pack (for a complete treatment series)
  • Reconstitution: With sterile water (5–8ml per vial, 24h before treatment)
  • Indications: Facial volume loss, deep nasolabial folds, cheeks, temples, chin
  • Injection Depth: Deep subcutaneous
  • Duration of Action: Up to 24 months

The Sculptra Treatment Protocol

  1. Session 1: First PLLA injection, massage protocol (5-5-5 rule)
  2. Session 2 (4–6 weeks later): Second injection, results begin to become visible
  3. Session 3 (optional, 4–6 weeks later): Third injection for maximum results
  4. Result: Fully visible after 3–6 months

The 5-5-5 Massage Rule

After each Sculptra injection, massage is crucial for even distribution and preventing nodules:

  • Massage for 5 minutes immediately after treatment
  • Massage 5 times a day
  • For 5 days after each session

Sculptra vs. Radiesse vs. Ellansé

Feature Sculptra (PLLA) Radiesse (CaHA) Ellansé M (PCL)
Immediate Effect No Yes (CMC) Yes (CMC)
Collagen Stimulation Very strong Medium Strong
Duration of Action Up to 24 months 12–18 months 24 months
Reversible No No No
Massage Protocol Yes (5-5-5) No No

Further Guides

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